Clinical Summary
Losing 50-100 hairs daily is normal. Seek evaluation for sudden hair loss, patches of complete baldness, hair loss with skin changes, or associated symptoms. Early treatment for androgenetic alopecia and autoimmune causes is most effective.
Urgent Indications
Seek prompt medical attention if:
- Sudden, rapid hair loss over days to weeks
- Hair loss with scalp symptoms - pain, burning, itching, scaling, redness
- Patches of complete baldness (alopecia areata)
- Hair loss with systemic symptoms - fever, weight loss, fatigue
- Scarring alopecia - permanent hair follicle destruction
Indications for Evaluation
Schedule an appointment if:
- Progressive thinning over months, especially if bothering you
- Family history of early baldness and you want early intervention
- Hair loss in unusual pattern (not typical male pattern)
- Associated symptoms - fatigue, weight changes, cold intolerance
- Recent medication changes or significant stress
- Age under 30 with noticeable thinning
Normal Hair Growth Cycle
- Anagen (growth phase): 2-6 years, 85-90% of scalp hair
- Catagen (transition): 2-3 weeks, follicle shrinks
- Telogen (resting): 2-4 months, then hair sheds
- Normal shedding: 50-100 hairs per day
- Total scalp hair: Approximately 100,000 follicles
Etiology
Androgenetic Alopecia (Male Pattern Baldness)
Most common cause - affects 50% of men by age 50:
- Mechanism: DHT (dihydrotestosterone) shrinks hair follicles
- Pattern: Receding hairline, thinning crown, eventual vertex balding
- Genetics: Hereditary - can inherit from either parent
- Progression: Gradual over years to decades
- Hamilton-Norwood scale: Classifies stages I-VII
Telogen Effluvium
Diffuse shedding 2-4 months after triggering event:
- Triggers: Major surgery, severe illness, high fever, childbirth, crash diets
- Medications: Beta-blockers, retinoids, anticoagulants, antidepressants
- Prognosis: Usually self-limited, regrows within 6-9 months
Alopecia Areata
Autoimmune condition causing patchy hair loss:
- Appearance: Round or oval patches of complete baldness
- Exclamation point hairs: Broken hairs at patch edges
- Variants: Alopecia totalis (entire scalp), universalis (entire body)
- Course: Unpredictable - may regrow spontaneously or progress
Medical Conditions
- Thyroid disorders: Hypothyroidism or hyperthyroidism
- Nutritional deficiencies: Iron, zinc, biotin, protein
- Autoimmune diseases: Lupus, dermatomyositis
- Infections: Fungal (tinea capitis), bacterial folliculitis
- Hormonal: Low testosterone, pituitary disorders
Diagnostic Evaluation
Physical Examination
- Pattern assessment: Distribution and extent of hair loss
- Pull test: Gentle traction to assess shedding
- Scalp examination: Inflammation, scaling, scarring
- Hair shaft examination: Miniaturization, breakage
Laboratory Testing
- Thyroid function: TSH, free T4
- Complete blood count: Rule out anemia
- Iron studies: Ferritin, iron, TIBC
- Testosterone levels: If symptoms suggest hormonal issues
- Scalp biopsy: If diagnosis uncertain or scarring suspected
Treatment Approaches
FDA-Approved Treatments for Male Pattern Baldness
- Minoxidil (Rogaine): Topical 5% foam or solution twice daily - stimulates growth, slows loss
- Finasteride (Propecia): Oral 1mg daily - blocks DHT conversion, 85% maintain/improve hair
- Timeline: Requires 6-12 months to see results, lifelong use to maintain
- Side effects: Finasteride - sexual dysfunction in 2-5%, usually reversible
Emerging Therapies
- Dutasteride: More potent DHT blocker (off-label use)
- Low-level laser therapy: FDA-cleared devices, modest efficacy
- Platelet-rich plasma (PRP): Injections to stimulate follicles
- Topical finasteride: Reduced systemic absorption
Surgical Options
- Hair transplantation: FUT (strip) or FUE (individual follicles)
- Best candidates: Stabilized hair loss, adequate donor hair
- Results: Natural-looking, permanent when done well
- Cost: $4,000-$15,000 depending on extent
Prevention and Hair Health
- Gentle hair care: Avoid excessive heat, tight hairstyles, harsh chemicals
- Balanced nutrition: Adequate protein, iron, biotin, zinc
- Stress management: Chronic stress contributes to telogen effluvium
- Sun protection: Wear hat to protect scalp
- Avoid smoking: Accelerates hair loss
- Early treatment: More effective before extensive loss occurs
Medical Review
Reviewed by: Ricardo Hamilton, MD
Last Updated: November 26, 2025
Sources: American Academy of Dermatology, International Society of Hair Restoration Surgery, FDA